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Publicaciones Lourdes Massieu Trigo
  • Monterrubio-Ledezma, F., Salcido-Gómez, A., Zavaleta-Vásquez, T., Navarro-García, F., Cisneros, B., & Massieu, L. (2025). The anti-senescence effect of D-?-hydroxybutyrate in Hutchinson-Gilford progeria syndrome involves progerin clearance by the activation of the AMPK-mTOR-autophagy pathway. GeroScience. https://doi.org/10.1007/s11357-024-01501-9
  • Castillo-Vazquez, S. K., Massieu, L., Rincón-Heredia, R., García-delaTorre, P., Quiroz-Baez, R., Gomez-Verjan, J. C., & Rivero-Segura, N. A. (2024). Glutamatergic Neurotransmission in Aging and Neurodegenerative Diseases: A Potential Target to Improve Cognitive Impairment in Aging. Archives of Medical Research, 55(6), 103039. https://doi.org/10.1016/j.arcmed.2024.103039
  • Gomora-Garcia JC; Montiel T; Htenrauch M; Salcido-Gomez A; Garcia-Velazquez L; Ramiro-Cortes Y; Gomora JC; Castro-Obregon S; Massieu L (2023). Effect of the Ketone Body, D-?-Hydroxybutyrate, on Sirtuin2-Mediated Regulation of Mitochondrial Quality Control and the Autophagy?Lysosomal Pathway Cells 12 (3) :486
  • Monterrubio-Ledezma F; Navarro-Garcia F; Massieu L; Mondragon-Flores R; Soto-Ponce LA; Magana JJ; Cisneros B (2023). Rescue of Mitochondrial Function in Hutchinson-Gilford Progeria Syndrome by the Pharmacological Modulation of Exportin CRM1 Cells 12 (2) :275
  • García-Velázquez, L., & Massieu, L. (2023). The proteomic effects of ketone bodies: implications for proteostasis and brain proteinopathies. Frontiers in Molecular Neuroscience, 16. https://doi.org/10.3389/fnmol.2023.1214092
  • Montiel T; Gómora-García JC; Gerónimo-Olvera C; Heras-Romero Y; Bernal-Vicente BN; Pérez-Martínez X; Tovar-y-Romo LB; Massieu L (2023). Modulation of the autophagy-lysosomal pathway and endoplasmic reticulum stress by ketone bodies in experimental models of stroke J NEUROCHEM 166 (1) :87-106
  • Morales-Rosales, S. L., Santín-Márquez, R., Posadas-Rodriguez, P., Rincon-Heredia, R., Montiel, T., Librado-Osorio, R., Luna-López, A., Rivero-Segura, N. A., Torres, C., Cano-Martínez, A., Silva-Palacios, A., Cortés-Hernández, P., Morán, J., Massieu, L., & Konigsberg, M. (2021). Senescence in Primary Rat Astrocytes Induces Loss of the Mitochondrial Membrane Potential and Alters Mitochondrial Dynamics in Cortical Neurons. Frontiers in Aging Neuroscience, 13. https://doi.org/10.3389/fnagi.2021.766306
  • Tovar?y?Romo, L. B., Massieu, L., & Arias, C. (2021). Ricardo Tapia (1940 ? 2021). Journal of Neurochemistry. doi:10.1111/jnc.15526
  • Gómora-García, J. C., Gerónimo-Olvera, C., Pérez-Martínez, X., & Massieu, L. (2021). IRE1? RIDD activity induced under ER stress drives neuronal death by the degradation of 14-3-3 ? mRNA in cortical neurons during glucose deprivation. Cell Death Discovery, 7(1). doi:10.1038/s41420-021-00518-9
  • Klionsky, D. J., Abdel-Aziz, A. K., Abdelfatah, S., Abdellatif, M., Abdoli, A., Abel, S., ? Acevedo-Arozena, A. (2021). Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1. Autophagy, 17(1), 1?382. doi:10.1080/15548627.2020.1797280
  • Torres-Esquivel, C., Montiel, T., Flores-Méndez, M., & Massieu, L. (2020). Effect of ?-Hydroxybutyrate on Autophagy Dynamics During Severe Hypoglycemia and the Hypoglycemic Coma. Frontiers in Cellular Neuroscience, 14. doi:10.3389/fncel.2020.547215
  • Montiel, T., Montes-Ortega, L. A., Flores-Yáñez, S., & Massieu, L. (2020). Treatment with the Ketone Body D-?-hydroxybutyrate Attenuates Autophagy Activated by NMDA and Reduces Excitotoxic Neuronal Damage in the Rat Striatum In Vivo. Current Pharmaceutical Design, 26(12), 1377?1387. doi:10.2174/1381612826666200115103646
  • Camberos-Luna, L., & Massieu, L. (2020). Therapeutic strategies for ketosis induction and their potential efficacy for the treatment of acute brain injury and neurodegenerative diseases. Neurochemistry International, 133, 104614. doi:10.1016/j.neuint.2019.104614
  • Moreno-Blas, D., Gorostieta-Salas, E., Pommer-Alba, A., Muciño-Hernández, G., Gerónimo-Olvera, C., Maciel-Barón, L. A., ? Castro-Obregón, S. (2019). Cortical neurons develop a senescence-like phenotype promoted by dysfunctional autophagy. Aging, 11(16), 6175?6198. doi:10.18632/aging.102181
  • Rivero-Segura, N. A., Coronado-Mares, M. I., Rincón-Heredia, R., Pérez-Torres, I., Montiel, T., Pavón, N., ? Cerbón, M. (2019). Prolactin prevents mitochondrial dysfunction induced by glutamate excitotoxicity in hippocampal neurons. Neuroscience Letters, 701, 58?64. doi:10.1016/j.neulet.2019.02.027
  • Languren, G., Montiel, T., Ramírez-Lugo, L., Balderas, I., Sánchez-Chávez, G., Sotres-Bayón, F., ? Massieu, L. (2017). Recurrent moderate hypoglycemia exacerbates oxidative damage and neuronal death leading to cognitive dysfunction after the hypoglycemic coma. Journal of Cerebral Blood Flow & Metabolism, 39(5), 808?821. doi:10.1177/0271678x17733640
  • Hernández-Espinosa, D. R., Massieu, L., Montiel, T., & Morán, J. (2019). Role of NADPH oxidase-2 in the progression of the inflammatory response secondary to striatum excitotoxic damage. Journal of Neuroinflammation, 16(1). doi:10.1186/s12974-019-1478-4
  • Gerónimo-Olvera C; Massieu L (2019). Autophagy as a Homeostatic Mechanism in Response to Stress Conditions in the Central Nervous System MOL NEUROBIOL 56 (9) :6594-6608
  • Nelson-Mora, J., Escobar, M. L., Rodríguez-Durán, L., Massieu, L., Montiel, T., Rodríguez, V. M., ? Gonsebatt, M. E. (2017). Gestational exposure to inorganic arsenic (iAs3+) alters glutamate disposition in the mouse hippocampus and ionotropic glutamate receptor expression leading to memory impairment. Archives of Toxicology, 92(3), 1037?1048. doi:10.1007/s00204-017-2111-x
  • Geronimo, C; Rincon-Heredia, R; Montiel, T; Castro-Obregon, S; Massieu, L (2017). Autophagy fails to prevent energy stress-induced neuronal death due to calpain-mediated lysosomal dysfuction JOURNAL OF NEUROCHEMISTRY 142 (SI) :250-251
  • Esquivel, M; Flores-Mendez, M; Montiel, T; Geronimo, C; Massieu, L (2017). Autophagy induction in brain by severe hypoglycemia and its modulation by the ketone body beta-hydroxybutyrate JOURNAL OF NEUROCHEMISTRY 142 (SI) :248-248
  • Massieu, L; Languren, G; Montiel, T; Ramirez-Lugo, L; Sanchez-Chavez, G; Sotres-Bayon, F; Bermudez-Rattoni, F (2017). Recurrent moderate hypoglycemia enhances brain injury induced by the hypoglycemic coma and leads to memory decline JOURNAL OF NEUROCHEMISTRY 142 (SI) :179-180
  • Gerónimo-Olvera, C., Montiel, T., Rincon-Heredia, R., Castro-Obregón, S., & Massieu, L. (2017). Autophagy fails to prevent glucose deprivation/glucose reintroduction-induced neuronal death due to calpain-mediated lysosomal dysfunction in cortical neurons. Cell Death & Disease, 8(6), e2911?e2911. doi:10.1038/cddis.2017.299
  • Rivero-Segura, N. A., Flores-Soto, E., García de la Cadena, S., Coronado-Mares, I., Gomez-Verjan, J. C., Ferreira, D. G., ? Cerbón, M. (2017). Prolactin-induced neuroprotection against glutamate excitotoxicity is mediated by the reduction of [Ca2+]i overload and NF-?B activation. PLOS ONE, 12(5), e0176910. doi:10.1371/journal.pone.0176910
  • Nelson-Mora, J., Massieu, L., Montiel, T., Escobar, M. L., Rodríguez-Durán, L., Rodríguez, V. M., & Gonsebatt, M. E. (2016). Gestational and chronical arsenic exposure generates changes in the hippocampus glutamatergic neurotransmission and plasticity. Toxicology Letters, 259, S203. doi:10.1016/j.toxlet.2016.07.486
  • Garza-Lombó, C., Massieu, L., Díaz, C., & Gonsebatt, M. E. (2016). Participation of MTOR in the transport of aminoacids involved in GSH synthesis in mouse brain. Toxicology Letters, 259, S200. doi:10.1016/j.toxlet.2016.07.478
  • García de la Cadena, S., & Massieu, L. (2016). Caspases and their role in inflammation and ischemic neuronal death. Focus on caspase-12. Apoptosis, 21(7), 763?777. doi:10.1007/s10495-016-1247-0
  • Gómez-López, S., Martínez-Silva, A. V., Montiel, T., Osorio-Gómez, D., Bermúdez-Rattoni, F., Massieu, L., & Escalante-Alcalde, D. (2016). Neural ablation of the PARK10 candidate Plpp3 leads to dopaminergic transmission deficits without neurodegeneration. Scientific Reports, 6(1). doi:10.1038/srep24028
  • Camberos-Luna, L., Gerónimo-Olvera, C., Montiel, T., Rincon-Heredia, R., & Massieu, L. (2015). The Ketone Body, ?-Hydroxybutyrate Stimulates the Autophagic Flux and Prevents Neuronal Death Induced by Glucose Deprivation in Cortical Cultured Neurons. Neurochemical Research, 41(3), 600?609. doi:10.1007/s11064-015-1700-4


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