Key to understanding the functions of the brain is to identify the dynamic synaptic interactions between the different neuronal sub-circuits while animals perform either goal directed or habitual actions. Our laboratory aim is to integrate a cross level approach (molecules – sub-circuits – behavior) to unravel the plastic synaptic and sub-circuits mechanisms that mediate the initiation/performance and switch between motor actions as well as the mechanisms modified when presenting neuropathological disorders such as in Parkinson’s and Huntington's disease, Tourette’s and obsessive compulsive disorders.



Striato-nigral pathway

ArchT-GFP Cre driven expression in D1 Cre mice

Instituto de Fisiología Celular, UNAM.

Circuito Exterior s/n, Ciudad Universitaria, Coyoacán, Distrito Federal, México.

Zip code: 04510

Phone (+52) 55 56225585

Striato-pallidal pathway

ArchT-GFP Cre driven expression in A2A Cre mice