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Martinon, Susana; Garcia-Vences, Elisa; Toscano-Tejeida, Diana; Flores-Romero, Adrian; Rodriguez-Barrera, Roxana; Ferrusquia, Manuel; Hernandez-Munoz, Rolando E; Ibarra, Antonio (2016)

LONG-TERM PRODUCTION OF BDNF AND NT-3 INDUCED BY A91-IMMUNIZATION AFTER SPINAL CORD INJURY

BMC Neurosci 17():
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After spinal cord (SC)-injury, a non-modulated immune response contributes to the damage of neural tissue. Protective autoimmunity (PA) is a T cell mediated, neuroprotective response induced after SC-injury. Immunization with neural-derived peptides (INDP), such as A91, has shown to promote-in vitro-the production of neurotrophic factors. However, the production of these molecules has not been studied at the site of injury.