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Escalera-Fanjul, Ximena; Quezada, Hector; Riego-Ruiz, Lina; Gonzalez, Alicia (2019)

WHOLE-GENOME DUPLICATION AND YEAST'S FRUITFUL WAY OF LIFE

Trends Genet. 35(1):42-54
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Studies on the fate of Saccharomyces cerevisiae paralogous gene pairs that arose through a whole-genome duplication event have shown diversification of retained duplicated genes. Paralogous functional specialization often results in improved function and/or novel function that could contribute to the adaptation of the organism to a new lifestyle. Here, we analyze and discuss particular case studies of paralogous functional diversification that could have played a role in the acquisition of yeast fermentative metabolism.