QR Code
Caligaris, Cassandre; Vazquez-Victorio, Genaro; Sosa-Garrocho, Marcela; Rios-Lopez, Diana G; Marin-Hernandez, Alvaro; Macias-Silva, Marina (2015)

ACTIN-CYTOSKELETON POLYMERIZATION DIFFERENTIALLY CONTROLS THE STABILITY OF SKI AND SNON CO-REPRESSORS IN NORMAL BUT NOT IN TRANSFORMED HEPATOCYTES

Biochim. Biophys. Acta 1850(9):1832-1841
full text

Ski and SnoN proteins function as transcriptional co-repressors in the TGF-β pathway. They regulate cell proliferation and differentiation, and their aberrant expression results in altered TGF-β signalling, malignant transformation, and alterations in cell proliferation.